SCHEMBL9160000

SCHEMBL9160000

COC(=O)NCCOc1ccc(Oc2cccc(Cl)c2)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.46
PPARD Q03181 2/20 0.45
PPARA Q07869 2/20 0.45
FAAH O00519 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
S1PR4 O95977 1/20 0.43
PPARG P37231 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TP53 P04637 1/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KLKB1 P03952 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9158327 0.91 PPARA (0.49) PPARDPPARAMEN1KMT2APKM
SCHEMBL9160265 0.90 HRH4 (0.43) MAPTPPARDPPARAMEN1KMT2A
SCHEMBL9163570 0.90 L3MBTL1 (0.45) MAPTPPARDPPARAFAAHMEN1
SCHEMBL9161447 0.89 HTT (0.54) MAPTPPARDPPARAFAAHMEN1
SCHEMBL9165644 0.89 PPARA (0.47) PPARDPPARAFAAHMEN1KMT2A
SCHEMBL9163556 0.88 PPARD (0.47) MAPTPPARDPPARAMEN1KMT2A
SCHEMBL9665380 0.88 FAAH (0.53) FAAHMEN1KMT2AKDM4ELMNA
SCHEMBL9163309 0.88 PPARD (0.43) MAPTPPARDPPARAFAAHMEN1
SCHEMBL9165605 0.88 TSHR (0.44) MAPTPPARDPPARAFAAHMEN1
SCHEMBL9165412 0.87 PPARA (0.46) PPARDPPARAFAAHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP claimed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US claimed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US disclosed