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Arginine

Arginine

SCHEMBL9164072

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.35
▸ MAOB P27338 1/20 0.35
▸ KDM5A P29375 1/20 0.35
▸ KDM1B Q8NB78 1/20 0.35
▸ VIPR2 P41587 9/20 0.32
▸ KEAP1 Q14145 1/20 0.32
▸ MAPK8 P45983 1/20 0.32
▸ MAPK9 P45984 1/20 0.32
▸ MAPK10 P53779 1/20 0.32
▸ VIPR1 P32241 7/20 0.32
▸ NPY2R P49146 5/20 0.31
▸ NPY4R P50391 5/20 0.31
▸ NPY5R Q15761 5/20 0.31
▸ NPY1R P25929 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL8203742 0.88 MAPK8 (0.32) MAPK8MAPK9MAPK10
Arginine SCHEMBL28532056 0.87 KDM1A (0.32) KDM1AMAOBKDM5AKDM1BNPY2R
Arginine SCHEMBL16279880 0.87 PRCP (0.33) KDM1AMAOBKDM5AKDM1BNPY2R
Arginine SCHEMBL28883128 0.87 PRCP (0.33) KDM1AMAOBKDM5AKDM1BNPY2R
Arginine SCHEMBL28033048 0.87 PRCP (0.33) KDM1AMAOBKDM5AKDM1BNPY2R
Arginine SCHEMBL6027855 0.87 PRCP (0.33) KDM1AMAOBKDM5AKDM1BNPY2R
Arginine SCHEMBL8200772 0.86 MAPK8 (0.34) MAPK8MAPK9MAPK10
Arginine SCHEMBL25171512 0.86 PRCP (0.33) —
Arginine SCHEMBL3195919 0.86 GSR (0.33) KDM1AMAOBKDM5AKDM1BNPY2R
Arginine SCHEMBL29151521 0.86 GSR (0.36) KDM1AMAOBKDM5AKDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0407544-B1 MONOCLONAL ANTIBODY AGAINST PROTEIN C OKLAHOMA MED RES FOUND (US) 1995-05-03 — — EP claimed