SCHEMBL9164073

SCHEMBL9164073

CCCCNC1CC(C)(C)N(C(C)=O)C(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 2/20 0.37
S1PR1 P21453 2/20 0.37
S1PR3 Q99500 2/20 0.37
S1PR5 Q9H228 1/20 0.33
GNAI3 P08754 2/20 0.33
GNAO1 P09471 2/20 0.33
GNAI1 P63096 2/20 0.33
GBA1 P04062 5/20 0.33
KMT2A Q03164 1/20 0.32
FUCA1 P04066 1/20 0.32
GLB1 P16278 1/20 0.32
FLT3 P36888 1/20 0.32
TYRO3 Q06418 1/20 0.32
MERTK Q12866 1/20 0.32
GAS6 Q14393 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9637959 0.90 KMT2A (0.32) KMT2A
SCHEMBL9491179 0.90 S1PR4 (0.36) S1PR4S1PR1S1PR3S1PR5GNAI3
SCHEMBL18591495 0.86 S1PR4 (0.35) S1PR4S1PR1S1PR3S1PR5GNAI3
SCHEMBL4023767 0.80 TSHR (0.43) S1PR4S1PR1S1PR3S1PR5KMT2A
SCHEMBL870336 0.80 GAA (0.38) S1PR4S1PR1S1PR3S1PR5GNAI3
SCHEMBL870335 0.80 S1PR4 (0.37) S1PR4S1PR1S1PR3S1PR5GNAI3
Hydrochloric Acid SCHEMBL9400298 0.79 TSHR (0.42) S1PR4S1PR1S1PR3GNAI3GNAO1
SCHEMBL870341 0.78 GNAI3 (0.37) S1PR4S1PR1S1PR3S1PR5GNAI3
SCHEMBL9861202 0.77 ALDH1A1 (0.33)
SCHEMBL9299461 0.77 POLB (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413665-B1 Polymer stabilizers containing both hindered amine and nitrone moieties CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
EP-0406825-B1 LUBRICANT COMPOSITION CIBA-GEIGY AG (CH) 1993-03-03 EP disclosed
EP-0413665-A2 Polymer stabilizers containing both hindered amine and nitrone moieties CIBA-GEIGY AG (CH) 1991-02-20 EP disclosed
EP-0406825-A1 Lubricant composition CIBA-GEIGY AG (CH) 1991-01-09 EP disclosed
US-4972009-A PHOTOSTABILIZERS FOR POLYMERS, RADIATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1990-11-20 US disclosed