SCHEMBL916415

SCHEMBL916415

Cc1nc2ccc(C#N)c(C#N)c2c(C#N)c1C#N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHFR P00374 1/20 0.35
▸ KDM4E B2RXH2 5/20 0.33
▸ ALDH1A1 P00352 5/20 0.32
▸ PKM P14618 2/20 0.32
▸ LRRK2 Q5S007 1/20 0.32
▸ NPSR1 Q6W5P4 3/20 0.31
▸ MAPT P10636 2/20 0.31
▸ TSHR P16473 1/20 0.31
▸ ADORA2A P29274 2/20 0.31
▸ HSD17B10 Q99714 2/20 0.31
▸ HTT P42858 2/20 0.31
▸ CYP1A2 P05177 2/20 0.31
▸ CYP2C9 P11712 2/20 0.31
▸ CYP2C19 P33261 2/20 0.31
▸ ADRA2A P08913 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ ADORA1 P30542 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ HIF1A Q16665 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL4266226 0.85 ALDH1A1 (0.44) KDM4EALDH1A1NPSR1MAPTTSHR
Potassium Ion SCHEMBL29058299 0.71 KDM5B (0.32) —
SCHEMBL29050226 0.71 KDM5B (0.32) —
SCHEMBL2162329 0.70 HSD17B10 (0.33) KDM4EALDH1A1NPSR1TSHRADORA2A
SCHEMBL3236023 0.69 HTT (0.39) KDM4EALDH1A1TSHRADORA2AHSD17B10
Hexamethylbenzene SCHEMBL4271177 0.67 TSHR (0.44) KDM4EALDH1A1TSHRHTTHPGD
SCHEMBL6059433 0.67 ALDH1A1 (0.68) KDM4EALDH1A1MAPTADORA2AHSD17B10
SCHEMBL19889994 0.66 MAP3K8 (0.35) KDM4EALDH1A1LRRK2NPSR1MAPT
SCHEMBL152358 0.66 TSHR (0.39) KDM4EALDH1A1MAPTTSHRHPGD
SCHEMBL31399295 0.66 TSHR (0.39) KDM4EALDH1A1MAPTTSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110988079-A In vitro diagnostic test strip preparation method and diagnostic test method 贾晓轻 2020-04-10 — — CN claimed
CN-110927225-A Electrochemical analysis in-vitro diagnostic test strip and diagnostic tester 贾晓轻 2020-03-27 — — CN claimed
JP-58059453-A — — None — — JP disclosed
EP-3837249-B1 SYNTHESIS OF CHROMANOL DERIVATIVES BASF SE (DE) 2025-04-02 — — EP disclosed
CN-112888678-B Synthesis of chromanol and 2-methyl-1, 4-naphthoquinone derivatives 巴斯夫欧洲公司 2025-03-07 — — CN disclosed
US-12168649-B2 Synthesis of chromanol and 2-methyl-1,4-naphthoquinone derivatives BASF SE (DE) 2024-12-17 — — US disclosed
CN-112888679-B Synthesis of chromanol derivatives 巴斯夫欧洲公司 2024-12-10 — — CN disclosed
CN-112839932-B Synthesis of Chromanol Derivatives 巴斯夫欧洲公司 2024-12-03 — — CN disclosed
US-12103918-B2 Synthesis of chromanol derivatives BASF SE (DE) 2024-10-01 — — US disclosed
EP-3837248-B1 SYNTHESIS OF CHROMANOL AND 2-METHYL-1,4-NAPHTHOQUINONE DERIVATIVES BASF SE (DE) 2024-07-24 — — EP disclosed
CN-116829563-A Cerium-ethylenediamine ketone and cerium-salen complexes and their use in organic electronics 克雷多西斯有限公司 2023-09-29 — — CN disclosed
EP-1206778-A1 CONDUCTING MATERIAL ABB AB (SE) 2002-05-22 — — EP disclosed
WO-2001075903-A1 CONDUCTING MATERIAL ABB AB (SE) 2001-10-11 — — WO disclosed
US-5840935-A Unsaturated polymerizable TTF, TCNQ and DCQDI monomers NORTHROP GRUMMAN CORPORATION (US) 1998-11-24 — — US disclosed
US-5834619-A Unsaturated polymerizable cyanoquinodimethane monomers NORTHROP GRUMMAN CORPORATION (US) 1998-11-10 — — US disclosed
US-5545703-A Electroconductive polymers from unsaturated polymerizable TTF, TCNQ and DCQDI monomers NORTHROP GRUMMAN CORPORATION (US) 1996-08-13 — — US disclosed
US-4735879-A SELECTIVELY CHANGING DOPANT CONCENTRATION IN ELECTROCONDUCTIVE POLYMER LAYER; VARIATIONS IN OPTICAL ABSORPTION MATSUSHITA ELECTRICAL INDUSTRIAL CO., LTD. (JP) 1988-04-05 — — US disclosed
EP-0134026-B1 A METHOD OF MANUFACTURING A MACROMOLECULAR MATERIAL CONDUCTING CURRENT ON ITS SURFACE POLSKA AKADEMIA NAUK CENTRUMBADAN MOLEKULARNYCH I MAKROMOLEKULARNYCH (PL) 1987-10-14 — — EP disclosed
US-4608192-A GRAPHITE INTERCALATED WITH ALKALI METAL, THEN ORGANIC ACID GTE LABORATORIES INCORPORATED (US) 1986-08-26 — — US disclosed
JP-S5859453-A ELECTROPHOTOGRAPHIC RECEPTOR RICOH CO LTD 1983-04-08 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12168649-B2 Synthesis of chromanol and 2-methyl-1,4-naphthoquinone derivatives CYP4B1, CYP2J2, CYP1A2 DHFR 2503/4885KDM4E 369/4885ALDH1A1 772/4885
US-12103918-B2 Synthesis of chromanol derivatives CYP4A11, CYP51A1, CYP8B1 DHFR 3745/4885KDM4E 827/4885ALDH1A1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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