SCHEMBL916488

SCHEMBL916488

O=P(O)(O)Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 3/20 0.58
PGK1 P00558 3/20 0.53
PGK2 P07205 3/20 0.53
ABCC4 O15439 1/20 0.52
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 1/20 0.52
PTGS1 P23219 1/20 0.52
HTT P42858 1/20 0.52
PTPN5 P54829 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21993641 1.00 ACP3 (0.58) ACP3PGK1PGK2ABCC4LMNA
SCHEMBL9407120 0.91 PGK1 (0.59) ACP3PGK1PGK2PTPN5
SCHEMBL24372954 0.89 ACP3 (0.49) ACP3PGK1PGK2ABCC4LMNA
SCHEMBL24372888 0.87 ACP3 (0.46) ACP3PGK1PGK2PTPN5
Benzylphosphonic Acid SCHEMBL44318 0.86 HPGD (0.60) ACP3PGK1PGK2TSHR
Benzylphosphonic Acid SCHEMBL11474641 0.84 HPGD (0.58) ACP3PGK1PGK2TSHR
Benzylphosphonic Acid SCHEMBL915222 0.84 HPGD (0.58) ACP3PGK1PGK2TSHR
Benzylphosphonic Acid SCHEMBL5332218 0.84 HPGD (0.58) ACP3PGK1PGK2TSHR
Benzylphosphonic Acid SCHEMBL11339355 0.84 HPGD (0.58) ACP3PGK1PGK2TSHR
Benzylphosphonic Acid SCHEMBL9182484 0.84 HPGD (0.58) ACP3PGK1PGK2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3935129-B1 LIGANDS FOR NANO-SIZED MATERIALS MERCK PATENT GMBH (DE) 2023-11-29 EP disclosed
US-20220127286-A1 LIGANDS FOR NANO-SIZED MATERIALS MERCK PATENT GMBH (DE) 2022-04-28 US disclosed
US-9902712-B2 Nitrogenous heterocyclic derivatives and their application in drugs SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-02-27 US disclosed
EP-3083584-B1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN THE TREATMENT OF TISSUE FIBROSIS SUNSHINE LAKE PHARMA CO LTD (CN) 2018-02-21 EP disclosed
US-20160355501-A1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS SUNSHINE LAKE PHARMA CO., LTD. (CN) 2016-12-08 US disclosed
CN-101208371-B Method for preparing polyester and polyester manufactured by the method as well as polyester formed body TOYO BOSEKI 2011-08-10 CN disclosed
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
EP-1842868-B1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT TOYO BOSEKI (JP) 2010-11-10 EP disclosed
US-20090082529-A1 Polyester, Process for Producing Polyester, and Polyester Molded Article TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
WO-1998054702-A1 MAGNETIC RECORDING MEDIA INCORPORATING SURFACE TREATED MAGNETIC PIGMENT IMATION CORP. (US) 1998-12-03 WO disclosed
US-5612352-A INHIBITORS OF SQUALENE SYNTHASE AND ANTICHOLESTEROL AGENTS WITH BIPHENYLQUINUCLIDINE DERIVATIVES ZENECA LIMITED (GB) 1997-03-18 US disclosed
EP-0625979-A1 AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1994-11-30 EP disclosed
EP-0526488-B1 BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS PFIZER (US) 1994-11-30 EP disclosed
US-5326905-A Benzylphosphonic acid tyrosine kinase inhibitors PFIZER INC. (US) 1994-07-05 US disclosed
EP-0596058-A1 BIPHENYLYLQUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS ZENECA LIMITED (GB) 1994-05-11 EP disclosed
WO-1993021184-A1 BIPHENYLYLQUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS ZENECA LIMITED (GB) 1993-10-28 WO disclosed
WO-1993015073-A1 AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1993-08-05 WO disclosed
EP-0526488-A1 BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS. PFIZER (US) 1993-02-10 EP disclosed
WO-1991015495-A1 BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS PFIZER INC. (US) 1991-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127286-A1 LIGANDS FOR NANO-SIZED MATERIALS L1CAM, EPCAM, SELPLG ACP3 1449/4885PGK1 4418/4885PGK2 4551/4885
US-20160355501-A1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS TNNC1, IAPP, TNNI3 ACP3 395/4885PGK1 2004/4885PGK2 2681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.