Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164585 | 0.87 | EBP (0.52) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL11346414 | 0.86 | EBP (0.67) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL9162747 | 0.85 | EBP (0.62) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL9161151 | 0.84 | EBP (0.58) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL9862828 | 0.84 | EBP (0.60) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL11462886 | 0.83 | SIGMAR1 (0.74) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL9815028 | 0.83 | SIGMAR1 (0.70) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL9124698 | 0.83 | MAPK1 (0.54) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL9162509 | 0.83 | SIGMAR1 (0.66) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL10929087 | 0.82 | SIGMAR1 (0.69) | EBPSIGMAR1ADORA3CHRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314879-A | Agriculture | Ministero Delli `Universita` E Della Ricerca Scientifica E Tecnologica (IT) | 1994-05-24 | — | — | US | claimed |
| EP-0444706-A2 | Aryl-propyl-amines having antifungal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1991-09-04 | — | — | EP | claimed |
| US-5378707-A | Applying to Erysiphe and/or Helminthosporium; agriculture | MINESTERO DELL' UNIVERSITA 'E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1995-01-03 | — | — | US | disclosed |
| EP-0444706-A2 | Aryl-propyl-amines having antifungal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1991-09-04 | — | — | EP | disclosed |