SCHEMBL9124698

SCHEMBL9124698

CC(CN1CC(C)OC(C)C1)Oc1ccc(OC[Si](C)(C)C)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 7/20 0.46
POLB P06746 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
SIGMAR1 Q99720 3/20 0.44
EBP Q15125 1/20 0.43
HTT P42858 2/20 0.42
ALDH1A1 P00352 6/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD3 P35462 1/20 0.41
KCNH2 Q12809 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9122286 0.85 MAPK1 (0.50) MAPK1L3MBTL1KDM4EPOLBTDP1
SCHEMBL9121486 0.85 MAPK1 (0.49) MAPK1L3MBTL1KDM4EPOLBTDP1
SCHEMBL9164899 0.83 EBP (0.64) MAPK1L3MBTL1KDM4EPOLBTDP1
SCHEMBL10610900 0.77 ADORA3 (0.51) MAPK1L3MBTL1KDM4EPOLBTDP1
SCHEMBL9122082 0.75 KDM4E (0.45) MAPK1L3MBTL1KDM4EPOLBTDP1
SCHEMBL9164585 0.75 EBP (0.52) MAPK1L3MBTL1KDM4EPOLBTDP1
SCHEMBL9125442 0.75 ALDH1A1 (0.49) MAPK1L3MBTL1KDM4EPOLBTDP1
SCHEMBL9124104 0.72 ALDH1A1 (0.47) MAPK1L3MBTL1KDM4EPOLBTDP1
SCHEMBL21202616 0.70 L3MBTL1 (0.79) MAPK1L3MBTL1KDM4EPOLBALDH1A1
SCHEMBL13033213 0.70 L3MBTL1 (0.97) MAPK1L3MBTL1KDM4EPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446873-B1 Amines showing fungicidal activity MINI RICERCA SCIENT TECNOLOG (IT) 1995-10-11 EP claimed
US-5385892-A Ethylamino phenyl ethers having antifungal activity MINISTERO DELL "UNIVERSITA" E DELL RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1995-01-31 US claimed
EP-0446873-A1 Amines showing fungicidal activity MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1991-09-18 EP claimed
JP-5310652-A None JP disclosed
US-5385892-A Ethylamino phenyl ethers having antifungal activity MINISTERO DELL "UNIVERSITA" E DELL RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1995-01-31 US disclosed
JP-H05310652-A AMINE DERIVATIVE HAVING ANTIFUNGAL ACTIVITY MINISTERO DELL UNIV E DELLA RIC SCIENT & TECNOL 1993-11-22 JP disclosed