Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163259 | 0.88 | NPC1 (0.52) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL9158337 | 0.87 | RAB9A (0.51) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL9163297 | 0.86 | NPC1 (0.50) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| Phenoxycarb SCHEMBL27336 | 0.84 | L3MBTL1 (0.62) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| Phenoxycarb SCHEMBL7944821 | 0.84 | L3MBTL1 (0.62) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL9156930 | 0.84 | NPC1 (0.50) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL4653234 | 0.82 | NPC1 (0.51) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| Phenoxycarb SCHEMBL6267309 | 0.81 | L3MBTL1 (0.58) | NPC1RAB9AHPGDCRHBPCRHR2 | |
| SCHEMBL9156942 | 0.81 | HPGD (0.45) | NPC1RAB9AHPGDL3MBTL1KDM4E | |
| SCHEMBL11425838 | 0.79 | L3MBTL1 (0.56) | NPC1RAB9AHPGDCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460472-B1 | Carbamic acid derivatives, their production and use | SUMITOMO CHEMICAL CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5346920-A | Insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0460472-A1 | Carbamic acid derivatives, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-12-11 | — | — | EP | disclosed |