Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 8/20 | 0.54 |
| ▸ | ITPR1 | Q14643 | 4/20 | 0.54 |
| ▸ | ITPR2 | Q14571 | 3/20 | 0.54 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133218 | 1.00 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL9742724 | 1.00 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL27550353 | 1.00 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL1356398 | 1.00 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL462454 | 1.00 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL1322462 | 1.00 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL7117013 | 1.00 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL639515 | 1.00 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL7171543 | 0.96 | ITPR3 (0.60) | ITPR3ITPR1ITPR2INPP5ASMPD1 | |
| SCHEMBL11233751 | 0.96 | ITPR3 (0.60) | ITPR3ITPR1ITPR2INPP5ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359257-B1 | Use of inositol triphosphate in the preparation of a medicament against diabetes | PERSTORP AB (SE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0359259-B1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF A MEDICAMENT AGAINST TRANSPLANTATION DISORDERS | PERSTORP AB (SE) | 1992-08-19 | — | — | EP | disclosed |
| US-5135923-A | Inositol triphosphate | PERSTORP AB (SE) | 1992-08-04 | — | — | US | disclosed |
| US-5051411-A | Administering inositol triphosphate for treatment of hypertension, immunodeficiency and dermatitis | PERSTORP AB (SE) | 1991-09-24 | — | — | US | disclosed |
| US-5023248-A | Hydroglycemic agents, treatment of hyperketonemia and changes in lipid metabolism | PERSTORP AB (SE) | 1991-06-11 | — | — | US | disclosed |
| US-5019566-A | Method of treating inflammation with inositol triphosphate | PERSTORP AB (SE) | 1991-05-28 | — | — | US | disclosed |
| US-5003098-A | Administering a Myo-Inositol Triphosphate | PERSTORP AB (SE) | 1991-03-26 | — | — | US | disclosed |
| EP-0359259-A2 | The use of inositoltrisphosphate for the preparing of a medicament against transplantation disorders | PERSTORP AB (SE) | 1990-03-21 | — | — | EP | disclosed |
| EP-0359257-A2 | Use of inositol triphosphate in the preparation of a medicament against diabetes | PERSTORP AB (SE) | 1990-03-21 | — | — | EP | disclosed |
| US-4851560-A | Inositol triphosphates | PERSTORP AB (SE) | 1989-07-25 | — | — | US | disclosed |
| US-4797390-A | REDUCE NEGATIVE EFFECTS OF CADMIUM OR ALUMINUM | PERSTORP AB (SE) | 1989-01-10 | — | — | US | disclosed |
| US-4793945-A | STABILIZING ORGANIC SUBSTRATE SUBJECT TO DEGRADATION BY OXIDATION AND-OR FREE RADICAL REACTION | PERSTORP AB (SE) | 1988-12-27 | — | — | US | disclosed |
| US-4794014-A | COUNTERACTING DELITERIOUS EFFECTS OF HEAVY METALS, RADIATION AND SMOKING | PERSTORP AB (SE) | 1988-12-27 | — | — | US | disclosed |