SCHEMBL1356398

SCHEMBL1356398

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nearest known ligand 0.74

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ITPR3 Q14573 8/20 0.54
ITPR1 Q14643 4/20 0.54
ITPR2 Q14571 3/20 0.54
INPP5A Q14642 2/20 0.52
SMPD1 P17405 1/20 0.50
INPPL1 O15357 1/20 0.46
AKT1 P31749 1/20 0.46
FDPS P14324 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7117013 1.00 ITPR3 (0.54) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL1322462 1.00 ITPR3 (0.54) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL133218 1.00 ITPR3 (0.54) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL9742724 1.00 ITPR3 (0.54) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL9165530 1.00 ITPR3 (0.54) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL639515 1.00 ITPR3 (0.54) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL462454 1.00 ITPR3 (0.54) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL27550353 1.00 ITPR3 (0.54) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL7171543 0.96 ITPR3 (0.60) ITPR3ITPR1ITPR2INPP5ASMPD1
SCHEMBL11233751 0.96 ITPR3 (0.60) ITPR3ITPR1ITPR2INPP5ASMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730460-B1 THE USE OF AN ESTER OF INOSITOLTRISPHOSPHATE FOR THE TREATMENT OF INFLAMMATORY CONDITIONS PERSTORP AB (SE) 2002-06-12 EP claimed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
WO-2025100535-A1 COOLING STRUCTURE AND BATTERY UNIT 日本製鉄株式会社 2025-05-15 WO disclosed
US-20240243386-A1 COOLING STRUCTURE, BATTERY UNIT, AND MANUFACTURING METHOD OF COOLING STRUCTURE NIPPON STEEL CORPORATION (JP) 2024-07-18 US disclosed
US-20240154208-A1 BATTERY UNIT NIPPON STEEL CORPORATION (JP) 2024-05-09 US disclosed
US-20240115595-A1 MATERIAL COMPOSITIONS AND METHODS OF USE IMPROVING RNA STABILITY TEAM MEDICAL, LLC (US) 2024-04-11 US disclosed
EP-4343926-A1 COOLING STRUCTURE, BATTERY UNIT, AND COOLING STRUCTURE MANUFACTURING METHOD NIPPON STEEL CORPORATION (JP) 2024-03-27 EP disclosed
WO-2024055011-A1 MATERIAL COMPOSITIONS AND METHODS OF USE IMPROVING RNA STABILITY TEAM MEDICAL, LLC (US) 2024-03-14 WO disclosed
CN-117651766-A Phytase variants with improved stability and IP4 activity 生化酶股份有限公司 2024-03-05 CN disclosed
CN-117642504-A Phytase variants 生化酶股份有限公司 2024-03-01 CN disclosed
US-4735902-A ORGANIC SUBSTRATES SUBJECT TO DEGRADATION BY OXIDATION OR FREE RADICALS PERSTORP AB (SE) 1988-04-05 US disclosed
US-4734283-A REMOVAL OF CADMIUM FROM BODY PERSTORP AB (SE) 1988-03-29 US disclosed
EP-0252227-A2 Use of inositol triphosphate in the treatment of metal intoxication PERSTORP AB (SE) 1988-01-13 EP disclosed
US-4718482-A FINS FOR AUTOMOBILE OR HOME AIR CONDITIONERS; SURFACE TREATED ALUMINUM MITSUBISHI ALUMINUM KABUSHIKI KAISHA (JP) 1988-01-12 US disclosed
EP-0179441-A2 A method of making a food composition containing inositoltriphosphate and the composition Sirén, Matti (CH) 1986-04-30 EP disclosed
EP-0179442-A2 Stabilized composition containing inositoltriphosphate and method for stabilizing the composition PERSTORP AB (SE) 1986-04-30 EP disclosed
EP-0179440-A1 Inositoltriphosphate, a method for preparing same and a composition containing same PERSTORP AB (SE) 1986-04-30 EP disclosed
EP-0179439-A1 A pharmaceutical composition and a method for preparing same Sirén, Matti (CH) 1986-04-30 EP disclosed
US-4265780-A PHOSPHORIC ACID ESTERS OF MYOINOSITOL NIPPON PAINT CO., LTD. (JP) 1981-05-05 US disclosed
US-4187127-A INOSITOL PHOSPHATE, A TITANIUM FLUORIDE NIHON PARKERIZING CO., LTD. (JP) 1980-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115595-A1 MATERIAL COMPOSITIONS AND METHODS OF USE IMPROVING RNA STABILITY RBM22, HNRNPUL2, HNRNPUL1 ITPR3 3547/4885ITPR1 3238/4885ITPR2 3622/4885
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 ITPR3 3393/4885ITPR1 2607/4885ITPR2 3424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.