Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158552 | 0.87 | GAA (0.37) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9254714 | 0.85 | PIK3CA (0.34) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9250851 | 0.80 | POLB (0.34) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9159849 | 0.78 | ALDH1A1 (0.33) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9255692 | 0.77 | TSHR (0.33) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9248313 | 0.69 | MEN1 (0.48) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9250855 | 0.67 | GAA (0.35) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9254724 | 0.67 | PIK3CA (0.35) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9255695 | 0.66 | ALDH1A1 (0.36) | POLBALDH1A1HTTLMNAHPGD | |
| SCHEMBL9168729 | 0.66 | POLB (0.35) | POLBALDH1A1HTTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434982-B1 | 5-(Amino)-triazolylcarbothioamide derivatives, process for their preparation and medicines containing them, as well as use of the former | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-03-15 | — | — | EP | disclosed |
| US-5276030-A | Tranquilizers, antispasmodics, antidepressants | EGIS GYOGYSZERGYAT (HU) | 1994-01-04 | — | — | US | disclosed |
| US-5175163-A | Tranquilizer, antidepresant, antispasmodic, analgesic and antiinflammatory agent | EGIS GYOGYSZERGYAR (HU) | 1992-12-29 | — | — | US | disclosed |
| EP-0434982-A2 | 5-(Amino)-triazolylcarbothioamide derivatives, process for their preparation and medicines containing them, as well as use of the former | EGIS GYOGYSZERGYAR (HU) | 1991-07-03 | — | — | EP | disclosed |