Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MTOR | P42345 | 4/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168729 | 0.91 | POLB (0.35) | GAAKDM4EHTTPIK3CAALDH1A1 | |
| SCHEMBL9255695 | 0.85 | ALDH1A1 (0.36) | GAAKDM4EHTTPIK3CAALDH1A1 | |
| SCHEMBL9254724 | 0.77 | PIK3CA (0.35) | GAAKDM4EHTTPIK3CAALDH1A1 | |
| SCHEMBL9248319 | 0.76 | MEN1 (0.46) | KDM4EHTTPIK3CAALDH1A1MTOR | |
| SCHEMBL9250851 | 0.75 | POLB (0.34) | GAAKDM4EHTTPIK3CAALDH1A1 | |
| SCHEMBL9159849 | 0.71 | ALDH1A1 (0.33) | GAAKDM4EHTTPIK3CAALDH1A1 | |
| SCHEMBL9258593 | 0.68 | GAA (0.41) | GAAKDM4EHTTPIK3CAALDH1A1 | |
| SCHEMBL9158552 | 0.67 | GAA (0.37) | GAAKDM4EHTTPIK3CAALDH1A1 | |
| SCHEMBL9165673 | 0.67 | POLB (0.39) | GAAKDM4EHTTPIK3CAALDH1A1 | |
| SCHEMBL7896518 | 0.66 | POLB (0.42) | GAAKDM4EHTTPIK3CAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434982-B1 | 5-(Amino)-triazolylcarbothioamide derivatives, process for their preparation and medicines containing them, as well as use of the former | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-03-15 | — | — | EP | disclosed |
| US-5175163-A | Tranquilizer, antidepresant, antispasmodic, analgesic and antiinflammatory agent | EGIS GYOGYSZERGYAR (HU) | 1992-12-29 | — | — | US | disclosed |
| EP-0434982-A2 | 5-(Amino)-triazolylcarbothioamide derivatives, process for their preparation and medicines containing them, as well as use of the former | EGIS GYOGYSZERGYAR (HU) | 1991-07-03 | — | — | EP | disclosed |