SCHEMBL9166017

SCHEMBL9166017

CCOC(C[SiH2]CCCl)OCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11265785 0.89
SCHEMBL703186 0.85 THRB (0.40) THRBLMNA
SCHEMBL319928 0.83 ALDH1A1 (0.36)
SCHEMBL28638892 0.82 THRB (0.42) THRBLMNA
SCHEMBL704452 0.80 THRB (0.36) THRBLMNA
SCHEMBL702536 0.80 THRB (0.36) THRBLMNA
SCHEMBL21332488 0.80 THRB (0.36) THRBLMNA
SCHEMBL6859233 0.78 THRB (0.35) THRBLMNA
SCHEMBL703875 0.77 THRB (0.38) THRBLMNA
SCHEMBL15194074 0.77 THRB (0.38) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5399739-A Method of making sulfur-containing organosilanes WRIGHT CHEMICAL CORPORATION (US) 1995-03-21 US disclosed
US-4507490-A SULFIDING A HALOALKYLORGANOSILANE DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-03-26 US disclosed
US-4129585-A NO FORMATION OF HYDROGEN SULFIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-12-12 US disclosed