Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517558 | 0.96 | PTGS2 (0.52) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL11794283 | 0.95 | PTGS2 (0.51) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29169558 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL22211304 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29169517 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL2760385 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL12645998 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL1784163 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL2049346 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL4557085 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596942-A | Azole derivative, process for producing azole derivative, and intermediate compound | KUREHA CORP | 2014-02-19 | — | — | CN | disclosed |
| EP-0571267-B1 | Use of azole derivatives for the preparation of drugs useful for inhibiting the aromatase and treating of estrogen-dependent diseases | KUREHA CHEMICAL IND CO LTD (JP) | 1995-04-26 | — | — | EP | disclosed |
| US-5286737-A | Benzyl, cyclopentane azole derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0571267-A1 | Use of azole derivatives for the preparation of drugs useful for inhibiting the aromatase and treating of estrogen-dependent diseases | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-11-24 | — | — | EP | disclosed |