Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784163 | 0.86 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29169558 | 0.86 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29169517 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL12645998 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL27604648 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL9147334 | 0.82 | PTGS1 (0.52) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL9166295 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL2049346 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL2760385 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL4557085 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210078941-A1 | Method For Preparing Substituted Phenylacetic Acid Derivative | JIANGSU RUIKE MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2021-03-18 | — | — | US | disclosed |
| EP-3680227-A1 | METHOD FOR PREPARING SUBSTITUTED PHENYLACETIC ACID DERIVATIVE | Jiangsu Ruike Medical Science And Technology Co., Ltd. (CN) | 2020-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078941-A1 | Method For Preparing Substituted Phenylacetic Acid Derivative | ALOX5, LOXL4, CYP3A5 | PTGS2 731/4885PTGS1 654/4885OPRK1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.