Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166526 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9160443 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9162712 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9160435 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9158682 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9158688 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9164440 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9164443 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL13125653 | 0.76 | HSD17B10 (0.47) | ALDH1A1KDM4EMAPTHPGDHTT | |
| SCHEMBL9166473 | 0.76 | MEN1 (0.42) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409952-A | Anticancer agents | ADIR ET COMPAGNIE (FR) | 1995-04-25 | — | — | US | disclosed |