Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166470 | 1.00 | MEN1 (0.42) | MEN1KMT2AAURKADAPK3MAP4K4 | |
| SCHEMBL9161742 | 0.83 | STING1 (0.58) | MEN1KMT2AGLASTING1KDM4E | |
| SCHEMBL9161739 | 0.83 | STING1 (0.58) | MEN1KMT2AGLASTING1KDM4E | |
| SCHEMBL9164874 | 0.81 | MCL1 (0.43) | MEN1KMT2AGLASTING1KDM4E | |
| SCHEMBL9164869 | 0.81 | MCL1 (0.43) | MEN1KMT2AGLASTING1KDM4E | |
| SCHEMBL8876534 | 0.79 | AURKA (0.49) | MEN1KMT2AAURKADAPK3MAP4K4 | |
| SCHEMBL8876466 | 0.77 | CYSLTR1 (0.44) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL8876470 | 0.77 | CYSLTR1 (0.44) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL9166526 | 0.76 | ALDH1A1 (0.61) | MEN1KMT2AAURKADAPK3MAP4K4 | |
| SCHEMBL9166530 | 0.76 | ALDH1A1 (0.61) | MEN1KMT2AAURKADAPK3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409952-A | Anticancer agents | ADIR ET COMPAGNIE (FR) | 1995-04-25 | — | — | US | disclosed |