Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166840 | 1.00 | PLA2G2A (0.58) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL9172779 | 0.96 | PLA2G2A (0.50) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL9172770 | 0.96 | PLA2G2A (0.50) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL9417612 | 0.94 | PLA2G2A (0.48) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL9417584 | 0.94 | PLA2G2A (0.65) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL9417386 | 0.94 | PLA2G2A (0.65) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL9417596 | 0.92 | PLA2G2A (0.62) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL9164435 | 0.89 | PLA2G2A (0.56) | PLA2G2ABLMPLA2G4BSMPD1CYP2D6 | |
| SCHEMBL9168861 | 0.87 | PLA2G2A (0.75) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL28531850 | 0.87 | PLA2G2A (0.75) | PLA2G2ABLMPPARAPLA2G4BSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446189-A | Diester intermediates for diacid enzyme inhibitor | HOFFMANN-LA ROCHE INC. (US) | 1995-08-29 | — | — | US | disclosed |