Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417386 | 1.00 | PLA2G2A (0.65) | PLA2G2ABLMPPARAPLA2G4BCYSLTR2 | |
| SCHEMBL9417596 | 0.98 | PLA2G2A (0.62) | PLA2G2ABLMPPARAPLA2G4BCYSLTR2 | |
| SCHEMBL9166846 | 0.94 | PLA2G2A (0.58) | PLA2G2ABLMPPARAPLA2G4BCYSLTR2 | |
| SCHEMBL9166840 | 0.94 | PLA2G2A (0.58) | PLA2G2ABLMPPARAPLA2G4BCYSLTR2 | |
| SCHEMBL9168861 | 0.93 | PLA2G2A (0.75) | PLA2G2ABLMPPARAPLA2G4BCYSLTR2 | |
| SCHEMBL28531850 | 0.93 | PLA2G2A (0.75) | PLA2G2ABLMPPARAPLA2G4BCYSLTR2 | |
| SCHEMBL9172779 | 0.89 | PLA2G2A (0.50) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL9172770 | 0.89 | PLA2G2A (0.50) | PLA2G2ABLMPPARAPLA2G4BSMPD1 | |
| SCHEMBL14611444 | 0.88 | PLA2G2A (0.66) | PLA2G2ABLMPPARAPLA2G4BCYSLTR2 | |
| SCHEMBL9417612 | 0.87 | PLA2G2A (0.48) | PLA2G2ABLMPPARAPLA2G4BSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |