Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169037 | 0.93 | ALDH1A1 (0.58) | NPSR1LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL9163642 | 0.91 | NPSR1 (0.56) | NPSR1LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL9168828 | 0.86 | ABCB1 (0.47) | NPSR1LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9168145 | 0.85 | NPSR1 (0.61) | NPSR1LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9168944 | 0.82 | ALDH1A1 (0.45) | NPSR1LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9563065 | 0.82 | ALDH1A1 (0.45) | NPSR1LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL9172377 | 0.82 | NPSR1 (0.45) | NPSR1LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL9231108 | 0.81 | NPSR1 (0.82) | NPSR1LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9172634 | 0.81 | NPSR1 (0.61) | NPSR1LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL9175257 | 0.77 | NPSR1 (0.52) | NPSR1LMNAALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | claimed |
| US-5405826-A | Herbicidal pyridopyridazinones and pyridopyridazinethiones | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | disclosed |