Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.38 |
| ▸ | CASP1 | P29466 | 7/20 | 0.38 |
| ▸ | CASP7 | P55210 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.38 |
| ▸ | USP2 | O75604 | 7/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172852 | 0.90 | DGAT2 (0.44) | ALDH1A1NPSR1LMNAKDM4ECYP1A2 | |
| SCHEMBL9169037 | 0.88 | ALDH1A1 (0.58) | ALDH1A1NPSR1LMNAKDM4ECYP1A2 | |
| SCHEMBL9170643 | 0.86 | NPSR1 (0.50) | ALDH1A1NPSR1LMNAKDM4ETRPA1 | |
| SCHEMBL9172377 | 0.83 | NPSR1 (0.45) | ALDH1A1NPSR1LMNAKDM4ESYK | |
| SCHEMBL9563065 | 0.83 | ALDH1A1 (0.45) | ALDH1A1NPSR1LMNAKDM4ESYK | |
| SCHEMBL9163642 | 0.83 | NPSR1 (0.56) | ALDH1A1NPSR1LMNAKDM4EMEN1 | |
| SCHEMBL9166887 | 0.82 | NPSR1 (0.55) | ALDH1A1NPSR1LMNAKDM4ECYP1A2 | |
| SCHEMBL9165448 | 0.76 | ALDH1A1 (0.57) | ALDH1A1NPSR1LMNAKDM4EMEN1 | |
| SCHEMBL9171888 | 0.75 | SLC5A1 (0.41) | ALDH1A1NPSR1LMNAKDM4EGRIN1 | |
| SCHEMBL9170308 | 0.75 | DGAT2 (0.43) | ALDH1A1NPSR1LMNAKDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | claimed |
| US-5405826-A | Herbicidal pyridopyridazinones and pyridopyridazinethiones | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | disclosed |