Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558156 | 0.82 | UPP1 (1.00) | UPP1 | |
| SCHEMBL9166276 | 0.81 | UPP1 (0.66) | UPP1 | |
| SCHEMBL9163320 | 0.80 | UPP1 (0.65) | UPP1 | |
| SCHEMBL9171945 | 0.79 | UPP1 (0.74) | UPP1 | |
| SCHEMBL9161543 | 0.77 | UPP1 (0.67) | UPP1 | |
| SCHEMBL3786418 | 0.77 | UPP1 (0.57) | UPP1USP2PNPTSHREDNRA | |
| SCHEMBL7516732 | 0.76 | UPP1 (0.77) | UPP1 | |
| SCHEMBL9169402 | 0.76 | UPP1 (0.66) | UPP1 | |
| SCHEMBL9171189 | 0.74 | UPP1 (0.67) | UPP1 | |
| SCHEMBL21067979 | 0.74 | UPP1 (0.74) | UPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649413-A1 | URACIL DERIVATIVES AS ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001414-A1 | URACIL DERIVATIVES AS ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-01-20 | — | — | WO | disclosed |