Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516732 | 0.88 | UPP1 (0.77) | UPP1DAO | |
| SCHEMBL21067979 | 0.86 | UPP1 (0.74) | UPP1 | |
| SCHEMBL9171945 | 0.86 | UPP1 (0.74) | UPP1 | |
| SCHEMBL9167311 | 0.82 | UPP1 (0.70) | UPP1 | |
| SCHEMBL9171189 | 0.81 | UPP1 (0.67) | UPP1 | |
| SCHEMBL9161543 | 0.81 | UPP1 (0.67) | UPP1DAO | |
| SCHEMBL30907672 | 0.81 | UPP1 (0.68) | UPP1DAO | |
| SCHEMBL8421019 | 0.81 | UPP1 (0.67) | UPP1DAO | |
| SCHEMBL9169468 | 0.80 | UPP1 (0.66) | UPP1 | |
| SCHEMBL9169402 | 0.80 | UPP1 (0.66) | UPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060985-A9 | COMPOSITIONS, METHODS AND KITS RELATING TO URIDINE PHOSPHORYLASE GENE MUTATIONS | UNIV YALE (US) | 2002-10-31 | — | — | WO | claimed |
| WO-2001060985-A2 | COMPOSITIONS, METHODS AND KITS RELATING TO URIDINE PHOSPHORYLASE GENE MUTATIONS | YALE UNIVERSITY (US) | 2001-08-23 | — | — | WO | claimed |
| US-12419893-B2 | Methods and compositions for maximizing the prevention and/or reduction of various maladies and drug side-effects using uridine | TOSK, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-12404304-B1 | Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same | SIERRA SCIENCES, LLC (US) | 2025-09-02 | — | — | US | disclosed |
| US-20250222000-A1 | Uridine Phosphorylase Inhibitors to Treat or Prevent Pulmonary Disease | TOSK, INC. | 2025-07-10 | — | — | US | disclosed |
| US-20250179122-A1 | Telomerase Reverse Transcriptase (TERT) Expression Enhancing Compounds and Methods for Using the Same | SIERRA SCIENCES, LLC | 2025-06-05 | — | — | US | disclosed |
| US-20250120956-A1 | Azole Compounds for Enhancing Telomerase Reverse Transcriptase (TERT) Expression | SIERRA SCIENCES, INC. | 2025-04-17 | — | — | US | disclosed |
| US-20250049834-A1 | Methods and Compositions for Treating Mucositis | TOSK, INC. | 2025-02-13 | — | — | US | disclosed |
| WO-2025019473-A1 | ISOXAZOLE-3-CARBOXYAMIDE COMPOUNDS FOR ENHANCING TELOMERASE REVERSE TRANSCRIPTASE (TERT) EXPRESSION | SIERRA SCIENCES, LLC (US) | 2025-01-23 | — | — | WO | disclosed |
| US-12194043-B2 | Uridine phosphorylase inhibitors to treat or prevent pulmonary disease | TOSK, INC. (US) | 2025-01-14 | — | — | US | disclosed |
| US-12168019-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | SIERRA SCIENCES, INC. (US) | 2024-12-17 | — | — | US | disclosed |
| EP-3042657-A1 | USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY INHIBITING THE HUMAN URIDINE PHOSPHORYLASE ENZYME | UNIÃO BRASILEIRA DE EDUCAÇAO E ASSISTÊNCIA- MANTENEDORA DA PUCRS (BR) | 2016-07-13 | — | — | EP | disclosed |
| US-20160193197-A1 | USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY INHIBITING THE HUMAN URIDINE PHOSPHORYLASE ENZYME | UNIÃO BRASILEIRA DE EDUCAÇÃO E ASSISTÊNCIA, MANTENEDORA DA PUCRS (BR) | 2016-07-07 | — | — | US | disclosed |
| WO-2001060985-A9 | COMPOSITIONS, METHODS AND KITS RELATING TO URIDINE PHOSPHORYLASE GENE MUTATIONS | UNIV YALE (US) | 2002-10-31 | — | — | WO | disclosed |
| WO-2001060985-A2 | COMPOSITIONS, METHODS AND KITS RELATING TO URIDINE PHOSPHORYLASE GENE MUTATIONS | YALE UNIVERSITY (US) | 2001-08-23 | — | — | WO | disclosed |
| US-5869467-A | VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1999-02-09 | — | — | US | disclosed |
| US-5641763-A | N-phosphonylmethoxyalkyl derivatives of pyrimdine and purine bases and a therapeutical composition therefrom with antiviral activity | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-06-24 | — | — | US | disclosed |
| US-5142051-A | Viricides special for mutants of herpes viruses | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-08-25 | — | — | US | disclosed |
| EP-0253412-B1 | N-PHOSPHONYLMETHOXYALKYL DERIVATIVES OF PYRIMIDINE AND PURINE BASES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREFROM WITH ANTIVIRAL ACTIVITY | Ceskoslovenska akademie ved (CS) | 1990-10-31 | — | — | EP | disclosed |
| EP-0253412-A2 | N-Phosphonylmethoxyalkyl derivatives of pyrimidine and purine bases, methods for their preparation and pharmaceutical compositions therefrom with antiviral activity | Ceskoslovenska akademie ved (CS) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12194043-B2 | Uridine phosphorylase inhibitors to treat or prevent pulmonary disease | UPP1, UMPS, PNP | UPP1 1/4885DAO 888/4885 |
| US-20250179122-A1 | Telomerase Reverse Transcriptase (TERT) Expression Enhancing Compounds and Methods for Using the Same | TERT, RNGTT, TERF2 | UPP1 211/4885DAO 1931/4885 |
| US-12419893-B2 | Methods and compositions for maximizing the prevention and/or reduction of various maladies and drug side-effects using uridine | UMPS, UNG, UGDH | UPP1 4/4885DAO 1907/4885 |
| US-20250049834-A1 | Methods and Compositions for Treating Mucositis | UNG, UMPS, TYMP | UPP1 7/4885DAO 2047/4885 |
| US-12168019-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | TERT, TERF2, RNGTT | UPP1 181/4885DAO 2627/4885 |
| US-12404304-B1 | Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same | TERT, TELO2, POT1 | UPP1 1627/4885DAO 1122/4885 |
| US-20250120956-A1 | Azole Compounds for Enhancing Telomerase Reverse Transcriptase (TERT) Expression | TERT, ERG, TERF2 | UPP1 444/4885DAO 875/4885 |
| US-20250222000-A1 | Uridine Phosphorylase Inhibitors to Treat or Prevent Pulmonary Disease | UPP1, UMPS, PNP | UPP1 1/4885DAO 888/4885 |
| US-20160193197-A1 | USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY INHIBITING THE HUMAN URIDINE PHOSPHORYLASE ENZYME | UPP1, PNP, TYMP | UPP1 1/4885DAO 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.