Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.51 |
| ▸ | FNTB | P49356 | 4/20 | 0.51 |
| ▸ | PTAFR | P25105 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167967 | 0.85 | PTAFR (0.64) | FNTAFNTBPTAFRHRH1 | |
| SCHEMBL18102086 | 0.82 | HRH1 (0.67) | FNTAFNTBPTAFRHRH1MEN1 | |
| SCHEMBL5060507 | 0.80 | SETD7 (0.59) | PTAFRHRH1MEN1KMT2A | |
| SCHEMBL6987747 | 0.77 | HRH1 (0.62) | FNTAFNTBPTAFRHRH1MEN1 | |
| SCHEMBL6991281 | 0.76 | HRH1 (0.43) | FNTAFNTBPTAFRHRH1 | |
| SCHEMBL6987948 | 0.76 | HRH1 (0.47) | FNTAFNTBPTAFRHRH1 | |
| Fumaric Acid SCHEMBL9239444 | 0.74 | MAPK1 (0.45) | FNTAFNTBPTAFRHRH1MEN1 | |
| SCHEMBL6995295 | 0.74 | HRH1 (0.43) | FNTAFNTBPTAFRHRH1 | |
| SCHEMBL9129563 | 0.74 | HRH1 (0.41) | FNTAFNTBPTAFRHRH1 | |
| Fumaric Acid SCHEMBL9239338 | 0.74 | MAPK1 (0.44) | FNTAFNTBPTAFRHRH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552292-B1 | SUBSTITUTED IMIDAZOBENZAZEPINES AND IMIDAZOPYRIDOAZEPINES | SCHERING CORP (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5393753-A | Antiallergens, antiinflammatory agents | SCHERING CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0552292-A1 | SUBSTITUTED IMIDAZOBENZAZEPINES AND IMIDAZOPYRIDOAZEPINES. | SCHERING CORP (US) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992006981-A1 | SUBSTITUTED IMIDAZOBENZAZEPINES AND IMIDAZOPYRIDOAZEPINES | SCHERING CORPORATION (US) | 1992-04-30 | — | — | WO | disclosed |