Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 12/20 | 0.64 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | FNTA | P49354 | 3/20 | 0.48 |
| ▸ | FNTB | P49356 | 3/20 | 0.48 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18102086 | 0.87 | HRH1 (0.67) | PTAFRHRH1FNTAFNTBSLC6A15 | |
| SCHEMBL9167320 | 0.85 | FNTA (0.51) | PTAFRHRH1FNTAFNTB | |
| SCHEMBL5060507 | 0.85 | SETD7 (0.59) | PTAFRHRH1 | |
| SCHEMBL6987948 | 0.81 | HRH1 (0.47) | PTAFRHRH1FNTAFNTB | |
| SCHEMBL9129563 | 0.81 | HRH1 (0.41) | PTAFRHRH1FNTAFNTB | |
| SCHEMBL6990659 | 0.81 | PTAFR (0.42) | PTAFRHRH1FNTAFNTBSLC6A15 | |
| SCHEMBL6988078 | 0.80 | SIGMAR1 (0.41) | PTAFRHRH1FNTAFNTB | |
| SCHEMBL6987747 | 0.79 | HRH1 (0.62) | PTAFRHRH1FNTAFNTB | |
| SCHEMBL6991281 | 0.79 | HRH1 (0.43) | PTAFRHRH1FNTAFNTB | |
| Fumaric Acid SCHEMBL9386969 | 0.79 | MAPK1 (0.43) | PTAFRHRH1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552292-B1 | SUBSTITUTED IMIDAZOBENZAZEPINES AND IMIDAZOPYRIDOAZEPINES | SCHERING CORP (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5393753-A | Antiallergens, antiinflammatory agents | SCHERING CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| WO-1992006981-A1 | SUBSTITUTED IMIDAZOBENZAZEPINES AND IMIDAZOPYRIDOAZEPINES | SCHERING CORPORATION (US) | 1992-04-30 | — | — | WO | disclosed |