Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP4 | P49662 | 1/20 | 0.43 |
| ▸ | CASP5 | P51878 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095595 | 0.82 | CASP1 (0.47) | CASP1CASP4CASP5ALOX5 | |
| SCHEMBL9806294 | 0.81 | CASP1 (0.46) | CASP1CASP4CASP5ALOX5 | |
| Hydrochloric Acid SCHEMBL9806239 | 0.80 | CASP1 (0.45) | CASP1CASP4CASP5ALOX5 | |
| SCHEMBL8653783 | 0.77 | CASP1 (0.43) | CASP1CASP4CASP5ALOX5 | |
| Hydrochloric Acid SCHEMBL10753020 | 0.76 | CASP1 (0.47) | CASP1CASP4CASP5ALOX5 | |
| SCHEMBL10995114 | 0.75 | CASP1 (0.42) | CASP1CASP4CASP5ALOX5 | |
| SCHEMBL10991452 | 0.75 | CASP1 (0.42) | CASP1CASP4CASP5ALOX5 | |
| Hydrochloric Acid SCHEMBL9208692 | 0.75 | ALOX5 (0.37) | CASP1CASP4CASP5ALOX5 | |
| Hydrochloric Acid SCHEMBL9208686 | 0.75 | ALOX5 (0.37) | CASP1CASP4CASP5ALOX5 | |
| SCHEMBL10506104 | 0.74 | CASP1 (0.40) | CASP1CASP4CASP5ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1033972-C | Cardioprotective tocopherol anologs | MERRELL DOW PHARMA (US) | 1997-02-05 | — | — | CN | disclosed |
| EP-0369874-B1 | Cardioprotective tocopherol analogs | MERRELL DOW PHARMA (US) | 1995-02-22 | — | — | EP | disclosed |
| CN-1042911-A | CARDIOPROTECTIVE TOCOPHEROL ANOLOGS | MERRELL DOW PHARMA (US) | 1990-06-13 | — | — | CN | disclosed |
| EP-0369874-A2 | Cardioprotective tocopherol analogs | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0369082-A1 | Cardioprotective tocopherol analogs | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |