SCHEMBL9168064

SCHEMBL9168064

O=[N+]([O-])c1ccc2[nH]nnc2c1O.[Ag]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 3/20 0.43
MAPT P10636 7/20 0.42
KDM4E B2RXH2 6/20 0.42
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
ALDH1A1 P00352 6/20 0.42
CTSB P07858 4/20 0.42
IDO1 P14902 2/20 0.42
TDO2 P48775 2/20 0.42
GAA P10253 1/20 0.42
LMNA P02545 4/20 0.39
TDP1 Q9NUW8 4/20 0.39
HTT P42858 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
HSP90AA1 P07900 3/20 0.39
CASP6 P55212 2/20 0.39
OPRK1 P41145 2/20 0.39
NPC1 O15118 1/20 0.39
BRD4 O60885 1/20 0.39
CHRM1 P11229 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6052169 0.98 GPR35 (0.44) GPR35MAPTKDM4EMEN1KMT2A
Silver SCHEMBL9168054 0.97 GPR35 (0.43) GPR35MAPTKDM4EMEN1KMT2A
SCHEMBL9169448 0.80 TDP1 (0.42) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL3728212 0.80 TSHR (0.37) GPR35MAPTKDM4EMEN1KMT2A
SCHEMBL32679425 0.80 TSHR (0.37) GPR35MAPTKDM4EMEN1KMT2A
SCHEMBL27647699 0.79 TDP1 (0.44) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL6970158 0.79 TDP1 (0.37) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL3730228 0.79 MAPT (0.40) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL6052000 0.78 TDP1 (0.43) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL8431464 0.78 GPR35 (0.49) GPR35MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0144087-B2 Heat-developable color light-sensitive material KONISHIROKU PHOTO IND (JP) 1995-05-24 EP disclosed
EP-0174135-B2 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1992-06-17 EP disclosed
EP-0144087-B1 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-18 EP disclosed
EP-0136142-B1 THERMALLY DEVELOPABLE, LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-11 EP disclosed
US-4840882-A CONTAINING A VINYL SULFONYL HARDENER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-20 US disclosed
EP-0174135-B1 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1989-04-26 EP disclosed
US-4770981-A MULTILAYER, DIFFUSION TRANSFER MATERIAL HAVING SPECIFIC BINDER CONCENTRATION; ANTIFOGGING AGENTS; COLOR SEPARATION; PHOTOTHERMOGRAPHY; DRY TREATMENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-09-13 US disclosed
US-4584267-A SILVER HALIDE, SILVER SALT, REDUCING AGENT, AND BINDER OF GELATIN OR DERIVATIVE AND POLYVINYL ALCOHOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-22 US disclosed
EP-0174135-A2 Heat-developable color light-sensitive material KONICA CORPORATION (JP) 1986-03-12 EP disclosed
EP-0157639-A2 Heat-developable multilayered color photo-sensitive material KONICA CORPORATION (JP) 1985-10-09 EP disclosed
US-4543309-A BENZOTRIAZOLE SILVER SALT, REDUCING AGENT, BINDER, AMINO-MERCAPTO TRIAZOLE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-24 US disclosed
EP-0144087-A2 Heat-developable color light-sensitive material KONICA CORPORATION (JP) 1985-06-12 EP disclosed
EP-0136142-A2 Thermally developable, light-sensitive material KONICA CORPORATION (JP) 1985-04-03 EP disclosed