SCHEMBL9168451

SCHEMBL9168451

CC(C1=CC=CC1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
GPR3 P46089 1/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
HTR2A P28223 1/20 0.33
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9165907 0.97 MEN1 (0.33) MEN1POLBKMT2AATMGPR3
Hydrochloric Acid SCHEMBL7940442 0.80 DNMT1 (0.32)
Hydrochloric Acid SCHEMBL6557718 0.80 MEN1 (0.40) MEN1POLBKMT2AATMCYP1A2
SCHEMBL27534312 0.79 CYP1A2 (0.33) GPR3CYP1A2TSHRHTR2ABCHE
SCHEMBL7052516 0.78 GPR3 (0.30) GPR3
SCHEMBL8584622 0.76 CYP1A2 (0.32) POLBCYP1A2TSHRSLC6A4SLC6A3
Hydrochloric Acid SCHEMBL8674458 0.76 CYP1A2 (0.32) CYP1A2TSHRBCHEACHE
Hydrochloric Acid SCHEMBL8674460 0.76 CYP1A2 (0.32) CYP1A2TSHRBCHEACHE
Hydrochloric Acid SCHEMBL6557720 0.76 GPR3 (0.34) MEN1POLBKMT2AATMGPR3
Hydrochloric Acid SCHEMBL9226884 0.75 SLC6A2 (0.32) SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1060176-C Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM CO (US) 2001-01-03 CN disclosed
US-5420320-A Method for preparing cyclopentadienyl-type ligands and metallocene compounds PHILLIPS PETROLEUM COMPANY (US) 1995-05-30 US disclosed