Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | CTSG | P08311 | 1/20 | 0.57 |
| ▸ | CTRC | Q99895 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365438 | 0.76 | F2 (0.67) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL6636236 | 0.75 | F2 (0.50) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL12927818 | 0.74 | F2 (1.00) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL6857906 | 0.74 | F2 (0.62) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL24186594 | 0.73 | F2 (0.55) | F2ELANECTSGCTRCALDH1A1 | |
| N-Ethylmaleimide SCHEMBL8835469 | 0.73 | MGLL (0.76) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL10134057 | 0.72 | F2 (0.60) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL2680644 | 0.68 | F2 (0.55) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL25165439 | 0.67 | F2 (0.52) | F2ELANECTSGCTRCALDH1A1 | |
| SCHEMBL13533522 | 0.65 | F2 (0.50) | F2ELANECTSGCTRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436260-A | Substituted 1-benzylimidazole-5-methylidene hydantoins | WARNER-LAMBERT COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| WO-1993013077-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |