Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617618 | 0.78 | AOC3 (0.49) | KDM4EL3MBTL1AOC3CASP1KMT2A | |
| SCHEMBL21668015 | 0.77 | L3MBTL1 (0.46) | KDM4EALDH1A1L3MBTL1CASP1LMNA | |
| SCHEMBL9168925 | 0.75 | CFD (0.46) | KDM4EALDH1A1L3MBTL1AOC3SMN1; SMN2 | |
| SCHEMBL16957110 | 0.74 | L3MBTL1 (0.44) | KDM4EALDH1A1L3MBTL1SMN1; SMN2CASP1 | |
| SCHEMBL1547567 | 0.73 | L3MBTL1 (0.59) | KDM4EALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL16961193 | 0.71 | L3MBTL1 (0.41) | KDM4EALDH1A1L3MBTL1CASP1FABP4 | |
| SCHEMBL3329675 | 0.70 | L3MBTL1 (0.49) | KDM4EALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2525928 | 0.70 | L3MBTL1 (0.62) | KDM4EALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL16959279 | 0.69 | L3MBTL1 (0.42) | KDM4EALDH1A1L3MBTL1SMN1; SMN2CASP1 | |
| SCHEMBL16950580 | 0.68 | L3MBTL1 (0.41) | KDM4EALDH1A1L3MBTL1SMN1; SMN2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651735-A1 | PHARMACOLOGICALLY ACTIVE ALPHA-(TERTIARY-AMINOMETHYL)-PHENYLMETHANOL DERIVATIVES | Pharmacia & Upjohn Aktiebolag (SE) | 1995-05-10 | — | — | EP | disclosed |