Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950776 | 0.85 | MEN1 (0.62) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8950880 | 0.83 | MEN1 (0.61) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL9163782 | 0.80 | GFER (0.66) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL8950913 | 0.79 | MEN1 (0.65) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL9168977 | 0.79 | NPC1 (0.52) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL9164150 | 0.78 | EPHX2 (0.52) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL23447836 | 0.77 | MEN1 (0.71) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL9167753 | 0.76 | MAPT (0.59) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL2682054 | 0.76 | KMT2A (1.00) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL15442327 | 0.76 | KMT2A (0.51) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519427-B1 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-04-26 | — | — | EP | disclosed |
| EP-0552418-A1 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0519427-A2 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |