Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NAAA | Q02083 | 2/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165612 | 0.87 | NAAA (0.50) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL9164417 | 0.86 | NAAA (0.64) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL9169489 | 0.82 | L3MBTL1 (0.50) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL30527282 | 0.81 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL9504178 | 0.81 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL6535660 | 0.81 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL10481026 | 0.81 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL845966 | 0.81 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL9265536 | 0.81 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDTHRATHRB | |
| SCHEMBL258708 | 0.81 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446189-A | Diester intermediates for diacid enzyme inhibitor | HOFFMANN-LA ROCHE INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0579066-A2 | N-substituted anilines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-19 | — | — | EP | disclosed |