Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91682 | 0.88 | NOTUM (0.31) | NOTUM | |
| SCHEMBL91828 | 0.87 | — | — | |
| SCHEMBL91783 | 0.84 | — | — | |
| SCHEMBL91713 | 0.84 | HSD11B1 (0.38) | PDE3BPDE3A | |
| SCHEMBL91707 | 0.83 | — | — | |
| SCHEMBL91768 | 0.81 | — | — | |
| SCHEMBL91830 | 0.81 | — | — | |
| SCHEMBL91769 | 0.79 | MAOB (0.32) | — | |
| SCHEMBL91738 | 0.79 | HSD11B1 (0.37) | — | |
| SCHEMBL91832 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |