Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91738 | 0.95 | HSD11B1 (0.37) | HSD11B1SLC6A3NISCH | |
| SCHEMBL91737 | 0.87 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL91683 | 0.86 | — | — | |
| SCHEMBL17548037 | 0.86 | HSD11B1 (0.37) | HSD11B1SLC6A3NISCHBRD4CREBBP | |
| SCHEMBL91744 | 0.84 | — | — | |
| SCHEMBL91771 | 0.84 | GRM2 (0.30) | — | |
| SCHEMBL91704 | 0.84 | GRM2 (0.36) | PDE3BPDE3A | |
| SCHEMBL13408479 | 0.83 | SLC6A2 (0.35) | HSD11B1SLC6A3 | |
| SCHEMBL91769 | 0.82 | MAOB (0.32) | — | |
| SCHEMBL17570167 | 0.81 | PDE3B (0.35) | HSD11B1SLC6A3NISCHBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |