Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230965 | 0.77 | FDPS (0.55) | METAP1ACP3CA12CA1CA2 | |
| SCHEMBL13327340 | 0.70 | FDPS (0.52) | METAP1ACP3CA12CA1CA2 | |
| SCHEMBL4104306 | 0.69 | METAP1 (0.49) | METAP1ACP3CA12CA1CA2 | |
| SCHEMBL1649220 | 0.68 | METAP1 (0.43) | METAP1ACP3CA12CA1CA2 | |
| SCHEMBL7435009 | 0.68 | METAP1 (0.51) | METAP1ACP3ANPEPERAP2 | |
| SCHEMBL7431441 | 0.68 | METAP1 (0.51) | METAP1ACP3ANPEPERAP2 | |
| SCHEMBL777378 | 0.68 | METAP1 (0.47) | METAP1ACP3CA12CA1CA2 | |
| SCHEMBL2331815 | 0.68 | METAP1 (0.50) | METAP1CA12CA1CA2MMP1 | |
| SCHEMBL10941895 | 0.66 | METAP1 (0.48) | METAP1ACP3CA12CA1CA2 | |
| Phosphoric Acid SCHEMBL11497465 | 0.66 | METAP1 (0.48) | METAP1ACP3CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650361-A1 | COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0642519-A1 | SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1994000130-A1 | COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1993024496-A1 | SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |