Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794337 | 0.97 | TSHR (0.38) | TSHR | |
| SCHEMBL18441001 | 0.83 | TSHR (0.48) | TSHR | |
| SCHEMBL12060642 | 0.81 | — | — | |
| SCHEMBL27843711 | 0.78 | DNM1 (0.41) | TSHR | |
| SCHEMBL28241820 | 0.77 | — | — | |
| SCHEMBL8772 | 0.76 | MAPK1 (0.42) | TSHR | |
| SCHEMBL27618767 | 0.76 | CA1 (0.35) | — | |
| SCHEMBL8039293 | 0.75 | OPRM1 (0.50) | TSHR | |
| SCHEMBL13446990 | 0.75 | — | — | |
| SCHEMBL11645650 | 0.75 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419283-B1 | Azlactone-functional silicon containing compounds and derivatives thereof | MINNESOTA MINING & MFG (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5147957-A | Pressure sensitive adhesives, release agents, elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0419283-A2 | Azlactone-functional silicon containing compounds and derivatives thereof | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-03-27 | — | — | EP | disclosed |
| EP-0186424-A2 | Acrylofunctional silicones | DOW CORNING CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4563539-A | ULTRAVIOLET CURABLE COATINGS | DOW CORNING CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |