Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490817 | 0.85 | KDM4E (0.46) | SLC2A1KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL14064624 | 0.85 | KDM4E (0.46) | SLC2A1KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28740512 | 0.84 | MAPT (0.46) | SLC2A1KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28975613 | 0.84 | TAAR1 (0.49) | SLC2A1KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28190293 | 0.84 | KDM4E (0.45) | SLC2A1KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8814573 | 0.83 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL5963023 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL9856949 | 0.80 | SLC2A1 (0.44) | SLC2A1KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6557781 | 0.80 | SLC2A1 (0.47) | SLC2A1KDM4EALDH1A1POLB | |
| SCHEMBL9749454 | 0.80 | SLC2A1 (0.44) | SLC2A1KDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584773-B2 | Phosphorous protecting groups and methods of preparation and use thereof | AGILENT TECHNOLOGIES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220002334-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2022-01-06 | — | — | US | disclosed |
| EP-0561948-B1 | PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | UPJOHN CO (US) | 1995-04-05 | — | — | EP | disclosed |
| EP-0622373-A1 | Phosphonic acid derivatives useful as anti-inflammatory agents | THE UPJOHN COMPANY (US) | 1994-11-02 | — | — | EP | disclosed |
| US-5360797-A | Bisphosphonic acid derivatives useful as anti-arthritic agents | THE UPJOHN COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| US-5298498-A | Antiarthritic agents | THE UPJOHN COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0561948-A1 | PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS. | UPJOHN CO (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010504-A2 | PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1992-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002334-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | POLN, POLRMT, NUDT21 | SLC2A1 3110/4885KDM4E 3963/4885ALDH1A1 3878/4885 |
| US-11584773-B2 | Phosphorous protecting groups and methods of preparation and use thereof | POLN, POLRMT, NUDT21 | SLC2A1 3110/4885KDM4E 3963/4885ALDH1A1 3878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.