Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6065450 | 0.86 | HTR2A (0.40) | HTR2A | |
| Hydrochloric Acid SCHEMBL9170197 | 0.86 | HTR2A (0.32) | HTR2A | |
| Hydrochloric Acid SCHEMBL9166987 | 0.84 | HTR2A (0.33) | HTR2AMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9163299 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL7642652 | 0.83 | HTR2A (0.40) | HTR2A | |
| Hydrochloric Acid SCHEMBL7939927 | 0.83 | HTR2A (0.40) | HTR2A | |
| SCHEMBL3994179 | 0.83 | HTR2A (0.42) | HTR2A | |
| SCHEMBL8439620 | 0.81 | HTR2A (0.41) | HTR2A | |
| Hydrochloric Acid SCHEMBL9066834 | 0.80 | HTR2A (0.40) | HTR2A | |
| Hydrochloric Acid SCHEMBL6560684 | 0.80 | HTR2A (0.40) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420320-A | Method for preparing cyclopentadienyl-type ligands and metallocene compounds | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-30 | — | — | US | disclosed |