SCHEMBL917064

SCHEMBL917064

CCOP(=O)(Cc1ccc(Cl)cc1)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 1/20 0.42
TSHR P16473 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 3/20 0.38
PTK2 Q05397 2/20 0.38
NPC1 O15118 1/20 0.38
CCNT1 O60563 2/20 0.38
CDK9 P50750 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
TDP1 Q9NUW8 4/20 0.37
NR1I2 O75469 1/20 0.37
TLR8 Q9NR97 1/20 0.37
TLR7 Q9NYK1 1/20 0.37
HDAC1 Q13547 1/20 0.37
MAPT P10636 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3375825 0.90 TSHR (0.50) NPY5RTSHRPOLBPTK2CCNT1
SCHEMBL11772418 0.87 PYCR1 (0.36) NPY5RTSHRMEN1KMT2APOLB
SCHEMBL3393833 0.85 NPY5R (0.42) NPY5RTSHRPOLBPTK2CCNT1
SCHEMBL20703788 0.84 KLK8 (0.48) NPY5RMEN1KMT2AGAAMAPT
SCHEMBL16062693 0.84 POLB (0.46) NPY5RTSHRPOLBCCNT1CDK9
SCHEMBL2493713 0.84 TSHR (0.44) NPY5RTSHRPOLBCCNT1CDK9
SCHEMBL9616093 0.84 MAPT (0.48) MEN1KMT2ANPC1KDM4EALDH1A1
SCHEMBL18392890 0.83 MEN1 (0.38) MEN1KMT2APOLBNPC1KDM4E
SCHEMBL914602 0.83 PPARD (0.42) MEN1KMT2APOLBNPC1KDM4E
SCHEMBL7164864 0.83 NPC1 (0.52) MEN1KMT2APOLBNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817430-A POLYARYLENEVINYLENE POLYMER XEROX CORPORATION (US) 1998-10-06 US claimed
US-20250298333-A1 POLYESTER RESIN COMPOSITION, ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, DEVELOPER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2025-09-25 US disclosed
CN-117980375-A Polycarbonate resin 三菱化学株式会社 2024-05-03 CN disclosed
US-RE49735-E1 Oxazolidinones as modulators of MGLUR5 BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-28 US disclosed
CN-116925032-A 1, 4-benzodioxane stilbene lignan compound, preparation method thereof and application thereof in resisting tumor 北京大学 2023-10-24 CN disclosed
WO-2023074576-A1 POLYCARBONATE RESIN 三菱ケミカル株式会社 2023-05-04 WO disclosed
CN-111171545-B Polycarbonate resin composition, method for producing same, and molded article 三菱化学株式会社 2023-04-28 CN disclosed
EP-4058435-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE Genentech, Inc. (US) 2022-09-21 EP disclosed
US-20220281819-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2022-09-08 US disclosed
CN-114728905-A Therapeutic compounds and methods of use 基因泰克公司 2022-07-08 CN disclosed
US-4886544-A PLANT GROWTH REGULATORS; ALKENYLATION, OXIDATION, HYDROLYSIS, ACYLATION, LACTONIZATION NIPPON KAYAKU KABUSHIKI KAISHA, A JOINT-STOCK COMPANY OF JAPAN (JP) 1989-12-12 US disclosed
US-4792567-A Acaricidal aryl arylthien-2-yl ethenes FMC CORPORATION (US) 1988-12-20 US disclosed
EP-0282984-A1 23-Phenylsteroids NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-09-21 EP disclosed
US-4611009-A Combating arthropods with 3-phenoxybenzyl 2,2-dimethyl-3-vinylcyclopropane carboxylates BAYER AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed
US-4423066-A MITICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0011695-B1 SUBSTITUTED CYCLOPROPANE CARBOXYLIC ACIDS AND THEIR DERIVATIVES; THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF INSECTICIDES AND ACARICIDES BAYER AG (DE) 1982-03-24 EP disclosed
US-4317782-A DYE LASERS, WHITENERS BAYER AKTIENGESELLSCHAFT (DE) 1982-03-02 US disclosed
US-4276306-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-06-30 US disclosed
EP-0011695-A1 Substituted cyclopropane carboxylic acids and their derivatives; their preparation and their use for the preparation of insecticides and acaricides BAYER AG (DE) 1980-06-11 EP disclosed
US-4057545-A FUNGICIDE, BACTERICIDE NORDMARK-WERKE GMBH HAMBURG (DT) 1977-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281819-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE VHL, NQO1, PCSK9 NPY5R 3803/4885TSHR 4511/4885MEN1 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.