Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | LSS | P48449 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27405797 | 0.82 | NPC1 (0.70) | HPGDALDH1A1MAPTGAAMEN1 | |
| SCHEMBL9130927 | 0.82 | LSS (0.90) | ALDH1A1MAPTTSHRLSSGAA | |
| SCHEMBL9129519 | 0.81 | LSS (0.76) | ALDH1A1MAPTLSSLMNATBXA2R | |
| SCHEMBL9130164 | 0.80 | TBXA2R (0.81) | ALDH1A1MAPTTBXA2RMEN1KMT2A | |
| SCHEMBL9754552 | 0.79 | MEN1 (0.84) | ALDH1A1TSHRLSSGAALMNA | |
| SCHEMBL9127709 | 0.79 | MEN1 (0.70) | ALDH1A1MAPTLSSGAALMNA | |
| SCHEMBL9129012 | 0.79 | LSS (0.72) | ALDH1A1MAPTLSSGAALMNA | |
| SCHEMBL3868846 | 0.79 | LSS (0.98) | ALDH1A1MAPTLSSLMNATBXA2R | |
| SCHEMBL9128739 | 0.78 | HTT (0.70) | HPGDALDH1A1MAPTGAALMNA | |
| SCHEMBL24324266 | 0.76 | HSD17B10 (0.55) | HPGDALDH1A1MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | claimed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |