Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129519 | 0.93 | LSS (0.76) | LSSKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9172903 | 0.89 | LSS (0.64) | LSSHRH3KCNH2 | |
| SCHEMBL9130927 | 0.89 | LSS (0.90) | LSSKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3868846 | 0.85 | LSS (0.98) | LSSKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9131391 | 0.85 | LSS (0.65) | LSSKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9754552 | 0.81 | MEN1 (0.84) | LSSKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7982901 | 0.80 | HRH3 (0.73) | ALDH1A1MBTD1L3MBTL1SIGMAR1HRH3 | |
| SCHEMBL9170751 | 0.79 | HPGD (0.75) | LSSKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10463570 | 0.78 | TBXA2R (0.80) | LSSKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9129895 | 0.78 | MEN1 (0.74) | LSSKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |