Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.90 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868846 | 0.96 | LSS (0.98) | LSSMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9129519 | 0.91 | LSS (0.76) | LSSMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9129012 | 0.89 | LSS (0.72) | LSSMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3868239 | 0.88 | LSS (0.72) | LSSMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9754552 | 0.84 | MEN1 (0.84) | LSSMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9131391 | 0.84 | LSS (0.65) | LSSMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9172903 | 0.83 | LSS (0.64) | LSS | |
| SCHEMBL9170751 | 0.82 | HPGD (0.75) | LSSMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL27587869 | 0.81 | LSS (0.62) | LSSKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL9484288 | 0.79 | LSS (0.59) | LSSMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |