Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916698 | 0.88 | SSTR5 (0.37) | PPARASSTR5PDE4DPDE4APDE4B | |
| SCHEMBL3547325 | 0.87 | GRM2 (0.32) | SSTR5PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL916709 | 0.86 | PDE4D (0.34) | SSTR5PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3674756 | 0.84 | SSTR5 (0.35) | SSTR5PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3945473 | 0.84 | PDE4D (0.35) | SSTR5PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL916902 | 0.84 | SSTR5 (0.40) | SSTR5PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3552800 | 0.83 | GRM2 (0.40) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3679289 | 0.83 | PDE4B (0.40) | PDE4DPDE4APDE4BPDE4CITGB1 | |
| SCHEMBL3945471 | 0.83 | PDE4D (0.34) | SSTR5PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL917952 | 0.82 | FPR2 (0.42) | SSTR5PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021473-A1 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED | 2011-01-27 | — | — | US | claimed |
| US-20110021473-A1 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021473-A1 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | PDE4A, PDE4B, PDE4C | PPARA 3224/4885SSTR5 3863/4885PDE4D 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.