Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.59 |
| ▸ | SLC16A3 | O15427 | 10/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729909 | 0.90 | FOLH1 (0.70) | FOLH1SLC16A3DHODHALDH1A1ALOX15 | |
| SCHEMBL9345842 | 0.88 | FOLH1 (0.68) | FOLH1SLC16A3DHODHALDH1A1ALOX15 | |
| SCHEMBL31474045 | 0.86 | FOLH1 (0.70) | FOLH1SLC16A3DHODHALDH1A1ALOX15 | |
| SCHEMBL1417089 | 0.85 | FOLH1 (0.59) | FOLH1SLC16A3DHODHALDH1A1ALOX15 | |
| SCHEMBL2777290 | 0.84 | FOLH1 (0.58) | FOLH1SLC16A3DHODHALDH1A1ALOX15 | |
| SCHEMBL11710027 | 0.83 | FOLH1 (0.61) | FOLH1SLC16A3ALDH1A1ALOX15TSHR | |
| SCHEMBL4907779 | 0.83 | FOLH1 (0.61) | FOLH1SLC16A3DHODHALDH1A1ALOX15 | |
| SCHEMBL9839456 | 0.83 | FOLH1 (0.61) | FOLH1SLC16A3DHODHALDH1A1ALOX15 | |
| SCHEMBL30365583 | 0.82 | FOLH1 (0.76) | FOLH1SLC16A3ALDH1A1ALOX15HMGB1 | |
| SCHEMBL70392 | 0.82 | FOLH1 (0.76) | FOLH1SLC16A3ALDH1A1ALOX15HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |