Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.58 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 10/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417089 | 0.98 | FOLH1 (0.59) | FOLH1DHODHSLC16A3HMGB1MAOA | |
| SCHEMBL9839456 | 0.93 | FOLH1 (0.61) | FOLH1DHODHSLC16A3HMGB1ALDH1A1 | |
| SCHEMBL9345842 | 0.91 | FOLH1 (0.68) | FOLH1DHODHSLC16A3HMGB1ALDH1A1 | |
| SCHEMBL729909 | 0.89 | FOLH1 (0.70) | FOLH1DHODHSLC16A3HMGB1ALDH1A1 | |
| SCHEMBL1257329 | 0.86 | FOLH1 (0.58) | FOLH1DHODHSLC16A3HMGB1ALDH1A1 | |
| SCHEMBL8366893 | 0.86 | MAPT (0.42) | FOLH1DHODHSLC16A3HMGB1MAOA | |
| SCHEMBL29690496 | 0.86 | MAPT (0.42) | FOLH1DHODHSLC16A3HMGB1MAOA | |
| SCHEMBL31484803 | 0.85 | HMGB1 (0.70) | FOLH1DHODHSLC16A3HMGB1ALDH1A1 | |
| SCHEMBL1449563 | 0.85 | HMGB1 (0.70) | FOLH1DHODHSLC16A3HMGB1ALDH1A1 | |
| SCHEMBL9809330 | 0.85 | HMGB1 (0.53) | FOLH1DHODHSLC16A3HMGB1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8431709-B2 | Acylation reaction of hydroxyl group | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2196451-A1 | ACYLATION REACTION OF HYDROXYL GROUP | Takasago International Corporation (JP) | 2010-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | FOLH1 3395/4885DHODH 540/4885SLC16A3 1062/4885 |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | FOLH1 3395/4885DHODH 540/4885SLC16A3 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.