Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619073 | 0.88 | AOC3 (0.49) | AOC3ALDH1A1MAPTDRD2ADRA2B | |
| SCHEMBL8619520 | 0.79 | ALDH1A1 (0.40) | AOC3ALDH1A1ACHEADRA2B | |
| SCHEMBL8618831 | 0.77 | AOC3 (0.44) | AOC3ALDH1A1MAPTDRD2ADRA2B | |
| SCHEMBL9387419 | 0.76 | AOC3 (0.37) | AOC3ALDH1A1MAPTADRA2BOPRK1 | |
| SCHEMBL8619187 | 0.75 | AOC3 (0.45) | AOC3ALDH1A1MAPTHTR2ASMN1; SMN2 | |
| SCHEMBL9173207 | 0.75 | ALDH1A1 (0.44) | AOC3ALDH1A1MAPTDRD2ADRA2B | |
| SCHEMBL8617684 | 0.74 | AOC3 (0.44) | AOC3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22620577 | 0.74 | ALDH1A1 (0.52) | AOC3ALDH1A1MAPTBCHETYR | |
| SCHEMBL12714862 | 0.74 | ALDH1A1 (0.52) | AOC3ALDH1A1MAPTBCHETYR | |
| SCHEMBL8619983 | 0.73 | AOC3 (0.39) | AOC3ALDH1A1MAPTBCHETYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651735-A1 | PHARMACOLOGICALLY ACTIVE ALPHA-(TERTIARY-AMINOMETHYL)-PHENYLMETHANOL DERIVATIVES | Pharmacia & Upjohn Aktiebolag (SE) | 1995-05-10 | — | — | EP | disclosed |