Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439054 | 0.77 | SMN1; SMN2 (0.38) | GAARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1290355 | 0.73 | HPGD (0.41) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28327759 | 0.73 | GAA (0.46) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27599916 | 0.71 | GAA (0.44) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2918163 | 0.71 | PIK3CD (0.49) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30839322 | 0.71 | GAA (0.41) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28805494 | 0.71 | GAA (0.45) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7599243 | 0.71 | GAA (0.38) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29818805 | 0.70 | KDM4E (0.41) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28264086 | 0.69 | ALDH1A1 (0.45) | GAANOTUMRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378373-A | Chelation with benzotriazolesulfonates | BETZ LABORATORIES, INC. (US) | 1995-01-03 | — | — | US | claimed |
| US-5378373-A | Chelation with benzotriazolesulfonates | BETZ LABORATORIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |