Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110899 | 0.69 | — | — | |
| SCHEMBL9114459 | 0.68 | GABRR1 (0.43) | TDP1ALDH1A1LMNA | |
| SCHEMBL9114483 | 0.68 | GABRR1 (0.43) | TDP1ALDH1A1LMNA | |
| SCHEMBL38940 | 0.68 | GABRR1 (0.43) | TDP1ALDH1A1LMNA | |
| SCHEMBL7609333 | 0.67 | ABAT (0.32) | — | |
| SCHEMBL12987958 | 0.63 | — | — | |
| SCHEMBL29160138 | 0.63 | — | — | |
| SCHEMBL638706 | 0.63 | — | — | |
| SCHEMBL24958749 | 0.63 | — | — | |
| SCHEMBL6791683 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459160-A | Antilipemic agents | TSUMURA & CO. (JP) | 1995-10-17 | — | — | US | disclosed |
| US-5374653-A | Iridoid derivatives and the use thereof as a drug | TSUMURA & CO. (JP) | 1994-12-20 | — | — | US | disclosed |
| US-5272172-A | Iridoid derivatives and the use thereof as a drug | TSUMURA & CO. (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0505572-A1 | IRIDOIDE DERIVATIVE AND ITS USE AS MEDICINE | TSUMURA & CO. (JP) | 1992-09-30 | — | — | EP | disclosed |