Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166799 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9173418 | 0.87 | PTGER1 (0.58) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9172122 | 0.87 | HPGD (0.52) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9172765 | 0.85 | PTGER1 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9169824 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9172155 | 0.85 | HPGD (0.49) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9157050 | 0.85 | MAPT (0.61) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9172644 | 0.84 | PTGER1 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL8798741 | 0.80 | SLC40A1 (0.44) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9172756 | 0.79 | HPGD (0.44) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420270-A | ANALGESICS; FOR TREATMENT OF PROSTAGLANDIN E2 MEDIATED DISEASES | G. D. SEARLE & CO. (US) | 1995-05-30 | — | — | US | claimed |
| US-5420270-A | ANALGESICS; FOR TREATMENT OF PROSTAGLANDIN E2 MEDIATED DISEASES | G. D. SEARLE & CO. (US) | 1995-05-30 | — | — | US | disclosed |