Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9173276 | 0.82 | HTT (0.47) | HSD17B10MAPTHTTCRHBPCRHR2 | |
| SCHEMBL8375398 | 0.80 | HSD17B10 (0.62) | HSD17B10MAPTHTTMEN1KMT2A | |
| SCHEMBL23855075 | 0.78 | HSD17B10 (0.48) | HSD17B10MAPTHTTMEN1KMT2A | |
| SCHEMBL5704226 | 0.78 | HSD17B10 (0.48) | HSD17B10MAPTHTTMEN1KMT2A | |
| SCHEMBL11355161 | 0.77 | CES2 (0.42) | HSD17B10MAPTHTTCRHBPCRHR2 | |
| SCHEMBL9862791 | 0.76 | MAPT (0.46) | HSD17B10MAPTHTTCRHBPCRHR2 | |
| SCHEMBL9175918 | 0.76 | HSD17B10 (0.41) | HSD17B10MAPTHTTCRHBPCRHR2 | |
| SCHEMBL11351332 | 0.76 | CA1 (0.43) | MAPTHTTCRHBPCRHR2MEN1 | |
| SCHEMBL8044565 | 0.76 | HSD17B10 (0.57) | HSD17B10MAPTHTTMEN1KMT2A | |
| SCHEMBL7119836 | 0.76 | HSD17B10 (0.52) | HSD17B10MAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386406-B1 | Polyhaloaromatic ester flame retardants for polyolefin resins | ATOCHEM NORTH AMERICA (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5086098-A | Polyhaloaromatic ester flame retardants for polyolefin resins | ATOCHEM NORTH AMERICA, INC. (US) | 1992-02-04 | — | — | US | disclosed |
| US-5043374-A | Improved flow characteristics during melt processing | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0386406-A1 | Polyhaloaromatic ester flame retardants for polyolefin resins | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4927873-A | Halophenyl ester flame retardants for polyphenylene ether resins | PENNWALT CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0333987-A2 | Halogenated polyester flame retardants for polyphenylene ether resins | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0333979-A1 | Halophenyl ester flame retardants for polyphenylene ether resins | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1989-09-27 | — | — | EP | disclosed |